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Active Drug Targeting by Receptor-Specific Ligands
Active targeting employs some strong interactions such as ligand-receptor or other molecular recognition to confer more specificity to the delivery system. The most important challenge in active targeting is to define the most suitable targeting agents to selectively and successfully transport nanoparticle systems to target tissue thus avoiding any kind of toxicity in the process. Peptides or receptor-ligands are used for targeting drugs to their specific receptors that are expressed profusely in different states of the disease.
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